Title: Enzymatic Catalysis in Presence of Cyclodextrins
VOLUME: 14 ISSUE: 13
Author(s):V. Bonnet, C. Gervaise, A. Favrelle, C. Sarazin and F. Djedaini-Pilard
Affiliation:Universite de Picardie Jules Verne, CNRS UMR 6219, Laboratoire des Glucides, Institut de Chimie de Picardie, 80039 Amiens, France.
Keywords:Cyclodextrin, Biocatalysis, Enzyme, Lyo-protectant, Refolding
Abstract: Cyclodextrins are able to interact in biocatalysis reaction. Their effects as solubilizing agents, inhibitor blocking agents and chiral selectors are well documented and they also interact before the enzyme-catalyzed reaction. Indeed, they have lyo-protectant effect for enzyme in organic medium biocatalysis and they participate in the refolding of inactive enzymes to regain their active form.