EGFR(S) Inhibitors in the Treatment of Gastro-Intestinal Cancers: Whats New?

Author(s): Shailender Singh Kanwar, Jyoti Nautiyal, Adhip P.N. Majumdar

Journal Name: Current Drug Targets

Volume 11 , Issue 6 , 2010

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In the past 10 to 15 years, a considerable progress has been made in the treatment of gastrointestinal (GI) related malignancies, as a number of agents expanded from only one in 1995 to seven in 2006. Current review describes the recent role of targeted therapies, specifically EGFR inhibitors in the treatment of GI cancers. Importance of dietary agents in the treatment and prevention of GI cancers is also reviewed.

Keywords: EGFR inhibitors, colon cancer, apoptosis

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Article Details

Year: 2010
Page: [682 - 698]
Pages: 17
DOI: 10.2174/138945010791170851
Price: $65

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