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Current Pharmaceutical Biotechnology

Editor-in-Chief

ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Thermal-Assisted Refolding: Dilution Folding Initiated at High Temperature

Author(s): Kentaro Shiraki and Soichiro Kayano

Volume 11, Issue 3, 2010

Page: [306 - 308] Pages: 3

DOI: 10.2174/138920110791111988

Price: $65

Abstract

Protein refolding from unfolded state is usually carried out at low temperature to reduce protein aggregation and proteolytic degradation. This review briefly introduces a unique method for the protein refolding via high temperature, typically at above melting temperature of the protein.

Keywords: Inclusion bodies, protein refolding

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