Title: Reduction of Sympathetic Hyperactivity by Agents that Inhibit the Renin Angiotensin Aldosterone System
VOLUME: 6 ISSUE: 2
Author(s):Laima Siddiqi and Peter J. Blankestijn
Affiliation:Department of Nephrology and Hypertension, University Medical Center, Room F03.226, PO Box 85500, 3508 GA Utrecht, the Netherlands.
Keywords:Sympathetic nerve hyperactivity, renin angiotensin aldosterone system
Abstract: This review describes the interactions between the renin-angiotensin and the sympathetic nervous system. Secondly, conditions and disease states particularly characterized by hyperactivity of the renin-angiotensin and/or the sympathetic nervous system will be discussed and finally evidence on the effects on the sympathetic nervous system of agents that inhibit the renin-angiotensin system and the significance of these findings in our understanding of the pathogenesis of sympathetic hyperactivity are summarized.
