Abstract
Wikstroemia indica (L.) C. A. Mey. is a member of family Thymelaeaceae and mainly distributes in middle and southeast part of China. As a traditional Chinese herb, this plant has long been employed as antipyretics, detoxicants, expectorants, vermifuges as well as aborticides in clinic practice. However, its use has mainly been based on empirical findings during hundreds and thousands of years. Recent studies indicated that W. indica contains abundant bioactive components including flavonoids, biflavonoids, coumarins, lignans, volatile oils, polysaccharides etc. This paper provides a comprehensive review of pharmacological relevant compounds of W. indica that have been characterized to date, and introduces the research progresses supporting its pharmacological action and clinical application. Particular attention has been given to antibacterial, antiviral, anti-inflammatory, anti-tumor and antifertility effects. Some examples of clinical applications of prepared W. indica in treatment of various diseases are outlined. Finally, the trend and necessity of future research, such as quantification of individual constituents extracted from W. indica and the assessment of their pharmacological activities in human body are proposed.
Keywords: Wikstroemia indica, bioactive components, pharmacological action, clinical application
Current Pharmaceutical Biotechnology
Title: Bioactive Components and Pharmacological Action of Wikstroemia indica (L.) C. A. Mey and Its Clinical Application
Volume: 10 Issue: 8
Author(s): Yan-Min Li, Liang Zhu, Jian-Guo Jiang, Li Yang and Ding-Yong Wang
Affiliation:
Keywords: Wikstroemia indica, bioactive components, pharmacological action, clinical application
Abstract: Wikstroemia indica (L.) C. A. Mey. is a member of family Thymelaeaceae and mainly distributes in middle and southeast part of China. As a traditional Chinese herb, this plant has long been employed as antipyretics, detoxicants, expectorants, vermifuges as well as aborticides in clinic practice. However, its use has mainly been based on empirical findings during hundreds and thousands of years. Recent studies indicated that W. indica contains abundant bioactive components including flavonoids, biflavonoids, coumarins, lignans, volatile oils, polysaccharides etc. This paper provides a comprehensive review of pharmacological relevant compounds of W. indica that have been characterized to date, and introduces the research progresses supporting its pharmacological action and clinical application. Particular attention has been given to antibacterial, antiviral, anti-inflammatory, anti-tumor and antifertility effects. Some examples of clinical applications of prepared W. indica in treatment of various diseases are outlined. Finally, the trend and necessity of future research, such as quantification of individual constituents extracted from W. indica and the assessment of their pharmacological activities in human body are proposed.
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Li Yan-Min, Zhu Liang, Jiang Jian-Guo, Yang Li and Wang Ding-Yong, Bioactive Components and Pharmacological Action of Wikstroemia indica (L.) C. A. Mey and Its Clinical Application, Current Pharmaceutical Biotechnology 2009; 10 (8) . https://dx.doi.org/10.2174/138920109789978748
DOI https://dx.doi.org/10.2174/138920109789978748 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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