Prosthetic Valve Endocarditis: Diagnostic Approach and Treatment Options

Author(s): Ioannis Starakis, Elias E. Mazokopakis

Journal Name: Cardiovascular & Hematological Disorders-Drug Targets
Formerly Current Drug Targets - Cardiovascular & Hematological Disorders

Volume 9 , Issue 4 , 2009

Become EABM
Become Reviewer
Call for Editor


Prosthetic valve endocarditis (PVE) is a grave medical entity with potentially fatal end results. The disease encompasses a rather small but, in the same time, vital part of IE incidents that is probable to be augmented in future years. PVE occurs in 1-4% of valve recipients during the first year following valve replacement, and in approximately 1 % per year afterwards. The type of prosthetic valve (mechanical versus bioprosthetic) seems not having an impact on the rate of development of IE and it is comparable in both groups (0.8 cases per year of follow-up). The pathogenetic mechanisms, pathogens implicated, clinical features and diagnostic approach of PVE will be reviewed here, along with the antibacterial and potential surgical treatment and prevention of the disease.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2009
Page: [249 - 260]
Pages: 12
DOI: 10.2174/1871529X10909040249
Price: $65

Article Metrics

PDF: 5