Assays for Eukaryotic Cell Chemotaxis

Author(s): Zac Pujic, Duncan Mortimer, Julia Feldner, Geoffrey J. Goodhill

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 12 , Issue 6 , 2009

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Abstract:

Chemotaxis is essential for many biological processes. Much of our understanding of the mechanisms underlying chemotaxis is based on a variety of in vitro assays. We review these assays, dividing them into groups depending on the process used to generate the gradient. We describe how each method works, its strengths and limitations, and provide some information about the kinds of cells that have been studied with each assay.

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Article Details

VOLUME: 12
ISSUE: 6
Year: 2009
Page: [580 - 588]
Pages: 9
DOI: 10.2174/138620709788681952
Price: $65

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