Cell Interactions with Biomaterials Gradients and Arrays

Author(s): Carl G. Simon Jr., Yanyin Yang, Vinoy Thomas, Shauna M. Dorsey, Abby W. Morgan

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 12 , Issue 6 , 2009

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Abstract:

Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and make useful substrates for fundamental studies of cell phenomena such as migration. This article will review the use of gradients and arrays in tissue engineering and biomaterials research, with a focus on cellular and biologic responses.

Keywords: Biomaterials, cell adhesion, cell-material interactions, combinatorial screening, gradient, hydrogel, microarray, polymer, tissue engineering

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Article Details

VOLUME: 12
ISSUE: 6
Year: 2009
Page: [544 - 553]
Pages: 10
DOI: 10.2174/138620709788681961
Price: $65

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