Synthetic Applications of Intramolecular Aza-Wittig Reaction for the Preparation of Heterocyclic Compounds

Author(s): Francisco Palacios, Domitila Aparicio, Gloria Rubiales, Concepcion Alonso, Jesus M. de los Santos

Journal Name: Current Organic Chemistry

Volume 13 , Issue 8 , 2009

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A review focused on recent advances in intramolecular aza-Wittig reaction of phosphazenes with several carbonyl or analogous compounds is reported. Phosphazenes afford intramolecular aza-Wittig reaction with different groups within the molecule as aldehydes, ketones, esters, thioesters, amides, anhydrides and sulfimides. One of the most important applications of this reaction is the synthesis of a wide range of heterocyclic compounds, ranging from simple monocyclic compounds to complex polycyclic and macrocyclic systems.

Keywords: Heterocyclic Compounds, synthesis, intramolecular aza-Wittig reaction, phosphazenes

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Article Details

Year: 2009
Page: [810 - 828]
Pages: 19
DOI: 10.2174/138527209788167196
Price: $58

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