Anti-Cancer Properties of Nigella spp. Essential Oils and their Major Constituents, Thymoquinone and β-Elemene

Author(s): Amr E. Edris

Journal Name: Current Clinical Pharmacology

Volume 4 , Issue 1 , 2009

Become EABM
Become Reviewer

Abstract:

Essential oils are the volatile fraction of aromatic and medicinal plants after extraction by steam or water distillation. They have been used for their pharmaceutical potential since early times, and even now are still subject to a great deal of attention, as is clear from the increasing number of publications each year on this subject. This review presents both fundamental and recent studies concerned with the role of Nigella species essential oils and their major constituents, thymoquinone and β-elemene, as potential chemotherapeutic and chemopreventive anti-cancer agents. The mechanism of action and the factors which determine the concentrations of these major constituents in the essential oil are also reviewed.

Keywords: Anti-cancer, essential oils, Nigella sativa, Nigella damascene, thymoquinone, β-elemene

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 4
ISSUE: 1
Year: 2009
Page: [43 - 46]
Pages: 4
DOI: 10.2174/157488409787236137

Article Metrics

PDF: 47