Analogues of Marine Pyrroloiminoquinone Alkaloids: Synthesis and Antitumor Properties

Author(s): Evelyne Delfourne

Journal Name: Anti-Cancer Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Volume 8 , Issue 8 , 2008


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Abstract:

Marine organisms provide a valuable source for natural products. In recent years, iminoquinone alkaloids including makaluvamines, isobatzellines, tsitsikammamines and wakayin, have emerged as an essential class of marine metabolites due to their prominent biological activities and unusual ring structures. This review focuses on synthesis and antitumor evaluation of analogues of these products.

Keywords: Pyrroloiminoquinone, makaluvamine, isobatzelline, tsitsikammamine, wakayin

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Article Details

VOLUME: 8
ISSUE: 8
Year: 2008
Page: [910 - 916]
Pages: 7
DOI: 10.2174/187152008786847710
Price: $65

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