Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine

Author(s): Alberto Coelho, Abel Crespo, Franco Fernandez, PierFrancesco Biagini, Angela Stefanachi, Eddy Sotelo

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 11 , Issue 10 , 2008


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Abstract:

Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.

Keywords: Supported reagents, TMG, base

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Article Details

VOLUME: 11
ISSUE: 10
Year: 2008
Page: [843 - 847]
Pages: 5
DOI: 10.2174/138620708786734253
Price: $65

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