Recent Applications of Microwaves in Synthesis of Bioactive Heterocyclic Compounds

Author(s): Rani Jindal, Sanjay Bajaj

Journal Name: Current Organic Chemistry

Volume 12 , Issue 10 , 2008

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Over the past decade, use of microwave energy, to heat chemical reactants on a laboratory scale, has evolved as a well-demonstrated alternative to traditional heating. Clean chemistry, reduction in reaction times, improved yields, and applicability to wide range of reactions, greatly improved efficiency with better quality, safety and tremendous scope for automation are some of the benefits of this emerging technology. Association of biological activity with heterocyclic motifs is well known and is important from drug discovery viewpoint. This article gives an account of the recent applications of microwaves in the synthesis of biologically active heterocyclic compounds with synthesis schemes and/or comprehensive review of reaction conditions and biological importance of over 50 such applications.

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Article Details

Year: 2008
Page: [836 - 849]
Pages: 14
DOI: 10.2174/138527208784911842
Price: $58

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