Abstract
Microarrays are a powerful tool has multiple applications both in clinical and cellular and molecular biology arenas. Early assessment of the probable biological importance of drug targets, pharmacogenomics, toxicogenomics and single nucleotide polymorphisms (SNPs). A list of new drug candidates along with proposed targets for intervention is described. Recent advances in the knowledge of microarrays analysis of organisms and the availability of the genomics sequences provide a wide range of novel targets for drug design. This review gives different process of microarray technologies; methods for comparative gene expression study, applications of microarrays in medicine and pharmacogenomics and current drug targets in research, which are relevant to common diseases as they relate to clinical and future perspectives.
Keywords: Microarrays, DNA arrays, gene expression, oligonucleotide, IHC, FISH, biomarker
Current Drug Metabolism
Title: Microarray: An Approach for Current Drug Targets
Volume: 9 Issue: 3
Author(s): Virendra S. Gomase, Somnath Tagore and Karbhari V. Kale
Affiliation:
Keywords: Microarrays, DNA arrays, gene expression, oligonucleotide, IHC, FISH, biomarker
Abstract: Microarrays are a powerful tool has multiple applications both in clinical and cellular and molecular biology arenas. Early assessment of the probable biological importance of drug targets, pharmacogenomics, toxicogenomics and single nucleotide polymorphisms (SNPs). A list of new drug candidates along with proposed targets for intervention is described. Recent advances in the knowledge of microarrays analysis of organisms and the availability of the genomics sequences provide a wide range of novel targets for drug design. This review gives different process of microarray technologies; methods for comparative gene expression study, applications of microarrays in medicine and pharmacogenomics and current drug targets in research, which are relevant to common diseases as they relate to clinical and future perspectives.
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Cite this article as:
Gomase S. Virendra, Tagore Somnath and Kale V. Karbhari, Microarray: An Approach for Current Drug Targets, Current Drug Metabolism 2008; 9 (3) . https://dx.doi.org/10.2174/138920008783884795
DOI https://dx.doi.org/10.2174/138920008783884795 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
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