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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Models for the Study of Angiogenesis

Author(s): Yuji Shiba, Masafumi Takahashi and Uichi Ikeda

Volume 14, Issue 4, 2008

Page: [371 - 377] Pages: 7

DOI: 10.2174/138161208783497741

Price: $65

Abstract

Cardiovascular disease remains a principal cause of mortality in Western countries. Novel strategies for enhancing angiogenesis (such as gene or cell therapy) provide alternative choices for patients without any current treatment options. This progress has contributed towards understanding the mechanisms underlying vascular formation. The establishment of new experimental models could lead to the development of new treatments. This article overviews the diverse models for the study of angiogenesis.

Keywords: Angiogenesis, vasculogenesis, endothelial progenitor cell, ischemia


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