Title: Rhodium-Catalyzed C-C Bond Cleavage Reactions
VOLUME: 11 ISSUE: 17
Author(s):David Necas and Martin Kotora
Affiliation:Department of Organic and Nuclear Chemistry, and Centre for Preparation and Application of Transition Metal Complexes, Faculty of Science, Charles University,Hlavova 8, 128 43 Praha 2, Czech Republic.
Keywords:Carbon Carbon bond, Cyclopropanes, Ring opening, Alkylidenecyclopropanes, Carbonylation, biphenylene
Abstract: Rhodium complexes have found a wide application in the catalytic C-C bond activation of various substrates depending on the ligand environment. The reaction proceeds with strained carbocycles (cyclopropanes, cyclobutanes and their derivatives), with non-strained C-C bonds activated by carbonyl or other functionalities, or it can result in decarbonylation (aldehydes, acyl halides etc.). Rhodium catalyzed C-C bond cleavage reactions were also used as key steps in syntheses of several natural compounds or biologically active molecules.
