New Chemical and Biological Aspects of S-Nitrosothiols

Author(s): K. Wang, W. Zhang, M. Xian, Y. C. Hou, X. C Chen, J. P. Cheng, P. G. Wang

Journal Name: Current Medicinal Chemistry

Volume 7 , Issue 8 , 2000


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Abstract:

Nitric oxide (NO) possesses many physiological effects and S-nitrosothiols have been identified in a variety of tissues exhibiting many NO-like activities. This review focuses on the latest discoveries pertaining to the biological functions of S-nitrosothiols and the recent research progress in the chemical properties and biomedical applications of RSNOs.

Keywords: S nitrosothiols, nitric oxide NO, RSNOs, superoxide catalzed RSNO, blood flow regulation, apotosis, platelet neutrophil interaactions, perinatal circulatory transition, S Nitroso 1 thiolsugars, TGSNO, S nitrosopeptides, Drug SNO conjugates, adrenergic receptor, Cu Zn superoxide dismutase, cardiac calcium release channel, cyclic nucleotide gated channel, interleukin converting enzyme, inducible nitric oxide synthase, xanthine oxidase, s Nitrosohemoglobin, disulfide, s Nitrosothiol, thiyl radical, glucopyranose

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Article Details

VOLUME: 7
ISSUE: 8
Year: 2000
Published on: 01 March, 2012
Page: [821 - 834]
Pages: 14
DOI: 10.2174/0929867003374633
Price: $65

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