17O-Isotope Labeling and Hydrogen-Bonded Structure Investigation in Peptides and Polypeptides by Solid State 17O NMR

Author(s): Shigeki Kuroki, Kazuo Yamauchi, Isao Ando, Akira Shoji, Takuo Ozaki

Journal Name: Current Organic Chemistry

Volume 5 , Issue 10 , 2001

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Most recent research works on the hydrogen-bonded structure of solid 17O-labeled peptides and polypeptides by means of solid -state 17O NMR are presented. It has been demonstrated that 17O-labeling andsolid -state 17O NMR provide useful informations about the hydrogen-bonded structure between the amide oxygen and proton of peptides and polypeptides in the solid state, in addition to 1H, 13C and 15N techniques.

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Article Details

Year: 2001
Page: [1001 - 1015]
Pages: 15
DOI: 10.2174/1385272013374914
Price: $58

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