Tumor Escape from Immune Response: Mechanisms and Targets of Activity

Author(s): Dmitry Gabrilovich, Vladimir Pisarev

Journal Name: Current Drug Targets

Volume 4 , Issue 7 , 2003

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Immune system plays an important role in control of tumor progression. Effective antitumor immune response depends on close interaction of several elements of immune system. They include antigen-presenting cells, different subsets of T cells, B cells and NK cells. However, tumor cells developed a number of mechanisms to escape recognition and elimination by immune system. In this review we will discuss these mechanisms and address possible approaches to correct them.

Keywords: Immune, tumor cells, antigen-presenting cells

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Article Details

Year: 2003
Page: [525 - 536]
Pages: 12
DOI: 10.2174/1389450033490849
Price: $65

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