Title: Gene Regulation in Cancer Gene Therapy Strategies
VOLUME: 10 ISSUE: 20
Author(s):Ian Scanlon, Panos Lehouritis, Ion Niculescu-Duvaz, Richard Marais and Caroline J. Springer
Affiliation:Cancer Research UK Centre for Cancer Therapeutics at the Institute of Cancer Research, 15Cotswold Road, Sutton, Surrey, SM2 5NG; UK
Keywords:transcriptional control, regulated expression, gdept, suicide gene
Abstract: Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.
