Title: New Multidrug Resistance Reversal Agents
VOLUME: 4 ISSUE: 1
Author(s):Masami Kawase and Noboru Motohashi
Affiliation:Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295,Japan
Keywords:Multidrug Resistance, chemotherapy, MDR phenotype, antitumor agents
Abstract: Multidrug resistance (MDR) to antitumor agents represents a significant challenge to effective chemotherapy. The use of MDR modulators is a promising approach to overcome the undesired MDR phenotype. The more effective MDR modulators are urgently needed for clinical use. This review focuses on literatures published in 1998-2001.