Abstract
This paper reviews progress towards the customised generation of proteins for applications as therapeutics, diagnostics and in proteomics. It particularly focuses on combinatorial approaches where proteins with pre-defined biochemical and biophysical characteristics are selected from large variant libraries.
Keywords: protein therapeutic, protein engineering, display, directed evolution, alternative frameworks
Current Pharmaceutical Biotechnology
Title: Combinatorial Protein Biochemistry for Therapeutics and Proteomics
Volume: 5 Issue: 1
Author(s): David Lowe and Lutz Jermutus
Affiliation:
Keywords: protein therapeutic, protein engineering, display, directed evolution, alternative frameworks
Abstract: This paper reviews progress towards the customised generation of proteins for applications as therapeutics, diagnostics and in proteomics. It particularly focuses on combinatorial approaches where proteins with pre-defined biochemical and biophysical characteristics are selected from large variant libraries.
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Cite this article as:
Lowe David and Jermutus Lutz, Combinatorial Protein Biochemistry for Therapeutics and Proteomics, Current Pharmaceutical Biotechnology 2004; 5 (1) . https://dx.doi.org/10.2174/1389201043489585
DOI https://dx.doi.org/10.2174/1389201043489585 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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