DNA Microarrays in Clinical Cancer Research

Author(s): Raymond Wadlow, Sridhar Ramaswamy

Journal Name: Current Molecular Medicine

Volume 5 , Issue 1 , 2005

Become EABM
Become Reviewer
Call for Editor


The recent sequencing of the human genome, coupled with advances in biotechnology, is enabling the comprehensive molecular “profiling” of human tissues. In particular, DNA microarrays are powerful tools for obtaining global views of human tumor gene expression. Complex information from tumor “expression profiling” studies can, in turn, be used to create novel molecular cancer diagnostics. We discuss the utility of DNA microarray-based tumor profiling in clinical cancer research, highlight some important recent studies, and identify future avenues of research in this evolving field.

Keywords: translocations, microarray-based gene expression, cdna, polymerase chain reaction, hybridization

open access plus

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2005
Page: [111 - 120]
Pages: 10
DOI: 10.2174/1566524053152834

Article Metrics

PDF: 16