Generic placeholder image

Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Discovery Strategies in a BioPharmaceutical Startup: Maximising your Chances of Success Using Computational Filters

Author(s): A. Jennings and M. Tennant

Volume 11, Issue 3, 2005

Page: [335 - 344] Pages: 10

DOI: 10.2174/1381612053382151

Price: $65

Abstract

Small research-based pharmaceutical start-ups often lack the budget and do not have the infrastructure available to apply all possible techniques for compound selection. This review details our use of a range of techniques such as high-throughput docking and similarity searching to maximize the success rate when attempting to identify pharmaceutically relevant ligands in a resource-constrained environment.

Keywords: docking methods, murein synthetic pathway, enzymes, murb assay, diversity metrics, pharmacophore


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy