Generic placeholder image

Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Disaccharide Nucleosides and their Incorporation into Oligonucleotides

Author(s): Ekaterina V. Efimtseva, Irina V. Kulikova and Sergey N. Mikhailov

Volume 11, Issue 4, 2007

Page: [337 - 354] Pages: 18

DOI: 10.2174/138527207780059367

Price: $65

Abstract

The review summarizes structural features, biological activity and synthetic methods of disaccharide nucleosides. In the first part the structures of natural disaccharide nucleosides are presented. The consequent part deals with general methods of synthesis of these compounds - formation of new N-and O-glycosidic bonds. Recent achievements in the preparation of disaccharide nucleosides from natural nucleosides are discussed. The last part is devoted to the synthesis and properties of oligonucleotides containing disaccharide nucleosides.

Keywords: poly(ADP-ribose), liposidomycins, disaccharide nucleoside antibiotic, Glucuronidation, O-glycosylation


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy