Abstract
Cell Transplantation is one of the powerful tools to ameliorate the capillary flow in ischemic condition. EPC (Endothelial Progenitor Cell) was identified in adult peripheral blood and thought to be a suitable candidate for cell transplantation. Also, gene therapy is already promising choice for enhancing angiogenic property. The combination of cell transplantation and gene therapy should be more effective way to regenerate vasculature in ischemic region. Recently, several research reports have come out regarding gene modified cell transplantation. We will mainly focus on the background of EPC, and then gene modified EPC findings in this review.
Keywords: Endothelial Progenitor Cell (EPC), Gene modified cell therapy, VEGF, TERT, Vasculogenesis
Current Gene Therapy
Title: Gene Modified Cell Transplantation for Vascular Regeneration
Volume: 7 Issue: 1
Author(s): Satoshi Murasawa and Takayuki Asahara
Affiliation:
Keywords: Endothelial Progenitor Cell (EPC), Gene modified cell therapy, VEGF, TERT, Vasculogenesis
Abstract: Cell Transplantation is one of the powerful tools to ameliorate the capillary flow in ischemic condition. EPC (Endothelial Progenitor Cell) was identified in adult peripheral blood and thought to be a suitable candidate for cell transplantation. Also, gene therapy is already promising choice for enhancing angiogenic property. The combination of cell transplantation and gene therapy should be more effective way to regenerate vasculature in ischemic region. Recently, several research reports have come out regarding gene modified cell transplantation. We will mainly focus on the background of EPC, and then gene modified EPC findings in this review.
Export Options
About this article
Cite this article as:
Murasawa Satoshi and Asahara Takayuki, Gene Modified Cell Transplantation for Vascular Regeneration, Current Gene Therapy 2007; 7 (1) . https://dx.doi.org/10.2174/1566523210707010001
DOI https://dx.doi.org/10.2174/1566523210707010001 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
Call for Papers in Thematic Issues
Programmed Cell Death Genes in Oncology: Pioneering Therapeutic and Diagnostic Frontiers (BMS-CGT-2024-HT-45)
Programmed Cell Death (PCD) is recognized as a pivotal biological mechanism with far-reaching effects in the realm of cancer therapy. This complex process encompasses a variety of cell death modalities, including apoptosis, autophagic cell death, pyroptosis, and ferroptosis, each of which contributes to the intricate landscape of cancer development and ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Chloride Channels − New Targets for the Prevention of Stroke
Current Vascular Pharmacology Garlic for Cardiovascular Disease: Prevention or Treatment?
Current Pharmaceutical Design Drug Delivery Systems with Modified Release for Systemic and Biophase Bioavailability
Current Clinical Pharmacology Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective Angioplasty; A Randomized Clinical Trial
Endocrine, Metabolic & Immune Disorders - Drug Targets The Fabry Cardiomyopathy - Diagnostic Approach and Current Treatment
Current Pharmaceutical Design The Aromatic Stacking Interactions Between Proteins and their Macromolecular Ligands
Current Protein & Peptide Science The Cardiac Microvasculature in Hypertension, Cardiac Hypertrophy and Diastolic Heart Failure
Current Vascular Pharmacology Gender Disparity in Lipid Target Achievements in High and Very High Atherosclerotic Cardiovascular Disease Risk Patients in the Arabian Gulf
Current Vascular Pharmacology The Significance of Meat in the Diet
Current Nutrition & Food Science Macrophages: Promising Targets for the Treatment of Atherosclerosis
Current Vascular Pharmacology The Perfect Storm: A Rheumatologist's Point of View on COVID-19 Infection
Current Rheumatology Reviews Nutrigenomic Analysis of Diet-Gene Interactions on Functional Supplements for Weight Management
Current Genomics MTHFR Gene Polymorphism and Diabetic Retinopathy
Current Diabetes Reviews Sudden Unexplained Death in Infancy and Long QT Syndrome
Current Pediatric Reviews Mediterranean Food Pattern in Rheumatoid Arthritis
Current Rheumatology Reviews Novel Oral Anticoagulants in Peripheral Arterial and Coronary Artery Disease
Cardiovascular & Hematological Agents in Medicinal Chemistry Pathophysiological Roles of Renin-Angiotensin System on Erythropoietic Action
Current Hypertension Reviews The Potential Role of Statins in Pneumonia
Current Respiratory Medicine Reviews Inflammation as a Therapeutic Target for Various Deadly Disorders: A Review
Current Drug Targets Advanced Tools of Regenerative Medicine for Neurodegenerative Diseases
Recent Patents on Regenerative Medicine