Insights into the Relationship Between Hypertension and Albuminuria

Author(s): Lucinda M. Hilliard, Leileata M. Russo, Wayne D. Comper

Journal Name: Current Hypertension Reviews

Volume 3 , Issue 1 , 2007

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Albuminuria is the increased excretion of the serum protein albumin into the urine. Albuminuria is classically seen as an important diagnostic marker of declining kidney function, however, more recently albuminuria has also been implicated as a marker for cardiovascular and peripheral vascular disease indicating an important link between processes governing both cardiovascular and renal function. This review will discuss i) a common mechanism for albuminuria that accounts for albuminuria seen in hypertension and other albuminuric states and ii) possible linking factors between albuminuria, hypertension and cardiovascular disease.

Keywords: Albumin, albuminuria, angiotensin II, cardiovascular disease, degradation pathway, hypertension, microalbuminuria, renin-angiotensin system, transforming growth factor-β1

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Article Details

Year: 2007
Published on: 01 March, 2012
Page: [29 - 37]
Pages: 9
DOI: 10.2174/157340207779815563

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PDF: 17