ISSN (Print): 1573-4110
ISSN (Online): 1875-6727
Volume 17, 9 Issues, 2021
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ISSN (Print): 1573-4110
ISSN (Online): 1875-6727
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Special Issue Submission
"Serious and independent sources of information such as Current Analytical Chemistry are desired and will expand the knowledge in qualitative as well as quantitative analytical operations."
Submit Abstract via Email
It was my first submission and my experience of working with Bentham Science Publishers remained excellent. I found prompt and supporting response at every step. I felt pleasure to share this wonderful experience with my colleagues. I am really grateful for whole team of Bentham Science Publishers for their timely support.
Muhammad Aslam Mirza (Department of Chemistry, Mirpur University of Science and Technology (MUST), Mirpur-10250 (AJK), Pakistan.)
Has contributed: Investigation of Antioxidant Activity and Trace Metals in Medicinal Plants in Kashmir, Pakistan.
10 Abstract Ahead of Print are available electronically
89 Articles Ahead of Print are available electronically
Green Analytical Chemistry principles are progressively applied in most analytical methods. Undoubtedly, environmental
analysis is one of the most relevant fields that should take care of the effects of the use of conventional methods and their impact
on the environment.
The scope of this special issue is to describe the state of the art in both analysis and sample pretreatment with regards to the
demands of green perspectives. Analytical scientists were invited to present their new strategies to fulfil all the requirements for
reduction of waste, energy consumption, use of solvents, etc.
Four comprehensive reviews are included in this mini thematic issue [1-4]. More specifically:
Amin et al., in their review “Recent Trends in Development of Green Analytical Methods for the Detection of Environmental
Pollutants using Nanomaterials”, provide information about multiple methods that use green nanomaterials for the analytical
assessment of environmental pollutants. UV-Vis spectrophotometry and electrochemical analysis using green and reproducible
nanomaterials are the major focus of this article. The authors conclude that the use of nanomaterials can drastically change the
detection limits due to the large surface area, strong catalytic properties, and tunable possibility. The used nanomaterials could
be washed, dried, and reused, which make the methods more proficient, cost-effective and environmentally friendly.
Erdem-Yayayürük and Yayayürük, in their review “Recent Advances in Environmental Analysis towards Green Nanomaterials”,
discuss strategies of green chemistry, green chemistry metrics, waste management, green nanotechnology/
nanoscience and characterization. The authors conclude that green synthesis of nanomaterials is a safer, energy-efficient and
fast method that reduces the use of solvent reagents and preservatives, which are hazardous to both environment and human
health. Moreover, the fabrication of nanomaterials using green procedures is a clean, safe, nontoxic, and environmentally
friendly method that increases its necessity and demand in large-scale applications.
Manousi and Zachariadis, in their review “Green Miniaturized Extraction and Microextraction of Polycyclic Aromatic Hydrocarbons
from Foods and Beverages”, discuss the recent advances in the extraction techniques of PAHs from food samples,
utilizing novel sample preparation approaches and adsorbents.
Compared to the traditional sample preparation techniques, the herein discussed green miniaturized extraction and microextraction
techniques offer multiple benefits, including simplicity, reduced sample preparation time, as well as reduced consumption
of organic solvents.
Tsalbouris et al., in their review “Recent advances in miniaturized microextraction techniques for the determination of bisphenols
in environmental samples: An overview of the last two decades”, discuss all recent advances in the development of
microextraction techniques, such as solid-phase extraction (SPE), solid-phase microextraction (SPME), magnetic solid-phase
microextraction (MSPE), liquid-phase microextraction (LPME), dispersive liquid-liquid microextraction (DLLME), stir bar
sorptive extraction (SBSE), matrix solid-phase dispersion (MSPD), that have been successfully applied in the extraction of bisphenols
from environmental matrices.
The analytical performance of the proposed techniques is critically discussed in this review, highlighting the potential and
limitations of each method.
The Guest Editor wishes to thank all the authors for their fine contribution.
This special issue of Current Analytical Chemistry titled “Imaging for analysis of materials and biological tissues” is dedicated
to the recent developments of advanced imaging methods in three different fields: Materials science, biomedicine, and
plant science. Traditional analytical techniques based on a single-point measurement provide satisfactory results when applied
to homogenous systems. However, most of the natural materials and biological tissues are inherently heterogeneous. Comprehensive
analysis of such materials requires imaging, where an additional spatial coordinate is added to a common analytical
tool to visualize variance within the subject. Given that biological tissue is inherently of low contrast, the addition of endogenous
probes or applying advanced techniques to improve the contrast is necessary. The objective of this special issue is to provide
a forum to present and collate significant and exciting studies involving contrast enhancement aspects of imaging to visualize
and understand critical biological phenomena. Thus this issue presents new exciting directions in the areas of contrast
probe development, instrumentation techniques, and image analysis toward applications in medicine and life science.
In their comprehensive review, a team of scientists led by Yongjian Liu  describes an emerging class of imaging agents
based on ultrasmall nanoclusters (USNCs). These promising imaging probes, typically with a core size less than 2 nm, have
drawn a great deal of attention due to the fact that they exhibit size-dependent physicochemical characteristics. Composed from
just a few hundreds of atoms, the majority of which are located on the surface of the nanocluster, USNCs emonstrate unusual
properties. Strong fluorescence emission and the ability to tune the emission to the near-infrared spectral range makes USNCs
attractive for optical imaging in live animals. Ultrasmall iron oxide NCs (IONCs), with a high ratio of surface magnetic Fe atoms,
are well suited for MRI imaging. Labeling the USNCs with radionuclides made these constructs excellent contrast agents
in positron emission tomography. Moreover, the ultra-small size of USNCs facilitates renal clearance, which is critical for the
development of non-toxic platforms for diagnostic and therapeutic applications.
In another review paper, Gabr and Pigge  describe an interesting class of luminogens that feature aggregation induced
emission (AIE). This class of molecules is typically non-emissive in solution but becomes highly luminescent upon aggregation.
Unlike conventional fluorophores that exhibit aggregation-caused quenching, AIE fluorophores exhibit strong turn-on
emission with low background signal. In addition, AIE fluorophores feature large Stokes’ shifts and excellent photostability –
highly essential and desired properties for efficient imaging. The flexible design of AIE emitters makes them an attractive fit
for a number of applications. The review describes the principles behind the design of the AIE bioprobes, from the detection of
amino acids and metals to imaging of mitochondria and other organelles. The review also discusses the use of AIE probes as a
new generation of diagnostics and therapeutics molecules.
Imaging that enables the assessment of the effect of stress on plants’ health and to predict and improve the crop yield is a
rapidly growing field in plant science. In order to address the need to remotely visualize freeze injury of plants in its earliest
onset, Peng and colleagues have developed a new method based on fluorescence lifetime imaging (FLIM) of leaves. In this
paper , the team explored the changes in the fluorescence lifetime of chlorophyll molecules in leaves. The authors have
demonstrated that the fluorescence lifetime of chlorophyll’s autofluorescence in intact leaves from a model plant periwinkle is
correlated with the degree of injury. The method shows a high sensitivity for detecting injury mere minutes after plant exposure
to -20oc, while no gross visual differences could be distinguished. Conventional color imaging, reflection, or and steady-state
fluorescence intensity showed lower sensitivity in detecting cold stress. The authors suggest that the proposed rapid, remote
method for quantitatively measuring cold stress in situ will aid in selecting cold-tolerant plants.
The papers presented in this focus thematic issue discuss novel challenges in imaging and present new directions. We believe
that the readers of Current Analytical Chemistry will find new stimulating ideas from this thematic issue, and we hope that this
issue will encourage researchers to develop novel imaging tools for biomedical and life science applications and beyond.
We would like to thank all the authors for their excellent contributions, the Editors of “Current Analytical Chemistry” for
this kind invitation to act as a guest editor for this thematic issue, and the valuable assistance by Editorial Manager Syed Faizan
Akhtar in the processing and finalization of this special theme issue.
The special issue entitled "Environmental Contamination, Toxicology, and Safety by Nanocatalysts", published in the
journal of "Current Analytical Chemistry" reports recent studies and applications of nanostructure and nanocomposite materials
for the environment. It is focused on recent research as well as reviews related to the preparation, characterization, and potential
applications of various doped and un-doped or intercalated nano-catalyst materials.
This topic is covering the promising research focusing on the detoxification of wastewater contaminants. It also covers the
advanced topics related to analytical and electrochemical methods covering the scope of various photo-catalysts as well as electro-
catalysts. It attracts the huge attention of scientists towards the development of the non-toxic, easy, ecofriendly way of
preparation-to-potential applications efficient catalyst on a broad scale. Nowadays, potentially unique research work on environmental
pollutants remediation offers various approaches for the development of semiconductor photo-catalyst nanomaterials
Recently, nanotechnology has developed semiconductor nanostructure materials at the nanoscale as well as nanodimensions
which facilitates the application of novel photo-catalytic or electro-catalytic materials in wastewater treatment. The
most dynamic area of photo-catalytic research is introduced with potential applications in areas such as sustainable detoxification
of toxic chemicals, healthcare safety, total mineralization of colored toxicants, and removal of heavy metal cations or anions.
In this issue [1-11], authors have contributed and discussed their findings in the areas such as the role of nano-photocatalysts
for detoxification of various heavy metals, the role of nano-catalyst for wastewater treatment, carbon-nitride based
noble advanced material for photocatalytic applications, nanotechnology-based solutions for wastewater treatment, TiO2 and
their modified forms for air pollution remediation, current development in nanostructure materials and composites for environmental
remediation, significance and antagonistic effect of nano-dimensional materials in sensing, nanostructure materials for
the detection of metallic ions from various effluents, the study on nanotechnology: food and environmental paradigm, and simple
and easy preparation of doped nanostructured materials with improved UV-photo-catalytic performances, etc.
We tried to discuss different kinds of analytical methods for detoxifying the organic and inorganic pollutants with various
hybrids, composites, and nanocomposites, and nanostructured materials. So, here we sincerely believe that this compiled thematic
issue would be very beneficial for the researchers who desire to gain comprehensive knowledge about environmental
remediation. It is also anticipated that this issue would be a useful collection for valuable readers from different parts of the
world. Hopefully, people will find scientific knowledge of photocatalysis from this complied thematic issue. We also hope that
this collection would encourage scientists as well as researchers to attain knowledge in environmental remediation of hazardous
and unsafe chemicals and ions by using different kinds of electro- and phot-chemical techniques.
Finally, we sincerely thank all authors for their excellent contributions as well as the Editors of “Current Analytical
Chemistry” for the kind invitation to act as guest editors for this special thematic issue.
This special issue of “Current Analytical Chemistry” journal, entitled “Photocatalyst for wastewater treatment” is
about the in-depth understanding of the relationship between the structure, the properties or the functions of different kinds of
photocatalytic material. This special issue combines different articles to explain the current work on wastewater treatment, synthesis,
characterization, and applications of the photocatalyst in wastewater treatment. To highlight the importance of photocatalyst,
this special issue reports on the current development in the photocatalyst approach to treat wastewater. Several influential
scientists contributed to share their ideas in this thematic issue. We would like to thank all of them for their valuable contributions
[1-9]. In this thematic issue, there exist seven review papers and two research papers. We tried to combine different
kinds of photocatalytic studies, discussed by various authors, to maintenance the riches of the water. Therefore, we believe that
this thematic issue will be beneficial for the readers who want to seek broad knowledge on this topic.
In this special issue of “Current Analytical Chemistry” journal, named “Current Analytical Techniques and Applications in
Pharmaceutical Analysis”, recent developments on drug analysis, some analytical techniques for pharmaceutical analyses such
as Ultra Performance Liquid Chromatographic Techniques, Box-Behnken Optimized Methodology, electrochemical techniques
etc., are discussed. This special issue includes two volumes, will combine not only different analyzing methods, to support the
prosperity of analytical chemistry, but also development of new researches on pharmaceutical analyses to support the importance
of pharmaceutical studies. Several important scientists contributed to share their ideas in this thematic issue. We
would like to thank them one by one for their valuable contributions.
In this thematic issue Volume I, there exist 7 review papers and 3 research papers. Nowadays, nanostructured materials have
a great variety of applications. Some of them are used in electrochemistry to modify electrodes. Subsequently, in this issue, the
first review, by P. Krzyczmonik and S. Skrzypek, addresses the “Composites of poly (3,4-ethylenedioxythiophene) with
nanostructures as electrochemical sensors for application in bioelectroanalysis” . “Recent progress in the analysis of captopril
using electrochemical Methods” are discussed by Mahesar et al. . In their review, some important applications of electrochemical
modes used for the analysis of captopril, the active pharmaceutical ingredient in antihypertensive drug has been
discussed. This review highlights the role of the analytical instrumentation, particularly electrochemical methods in assessing
captopril using various working electrodes. In another review paper, Fatma Ağın shared researches about “Electroanalytical
methods for determination of calcium channel blockers” . This review mainly includes recent determination studies of calcium
channel blockers by electroanalytical methods from pharmaceutical dosage forms and biological samples, as calcium channel
blockers are widely used in treatment of cardiovascular heart diseases in recent years.
Furthermore, “Electrochemical sensors based on molecularly imprinted polymers for pharmaceuticals analysis” topic is well
discussed by the authors Radi et al. . This review discussed the development of chemical sensing of drugs in pharmaceutical
formulations and biological matrices using Molecular-Imprinting Polymer (MIP) as a recognition element combined with different
electrochemical signal transduction. The MIP electrochemical sensors based on nanomaterials such as graphene, carbon
nanotubes, nanoparticles, as well as other electrode modifiers incorporated into the MIPs to enhance the sensors performance,
have been reviewed.
In another review contribution, entitled as “Voltammetric analysis of atypical antipsychotic drugs with solid electrodes” has
found place by Dilek Kul . This review presents voltammetric methods used for the determination of some electrochemically
active atypical antipsychotic drugs, which are amisulpride, aripiprazole, clozapine, olanzapine, quetiapine fumarate, risperidone,
sertindole, and ziprasidone, in pure solutions, pharmaceutical dosage forms and biological samples using various unmodified
and modified solid electrodes. Another interesting review paper suggested by Srivastava et al., entitled as “Voltammetric
techniques for the analysis of drugs using nanomaterials based chemically modified electrodes” . Their paper focuses solely
on application of electroanalytical techniques for individual and simultaneous analysis of drugs as well as in pharmaceutical
formulations of dosage forms and biological media such as blood serum, urine, etc. for various classes of drugs such as analgesics,
anti-helmentics, anti-tuberculosis, cardiovascular, antipsychotics, anti-allergic, antibiotics and gastro-intestinal.
Besides, Kurbanoglu et al., contributed to this thematic issue with a motivating review paper entitled as “Recent advances on
drug analyses using Ultra Performance Liquid Chromatographic (UPLC) techniques and their application to the biological
samples” . The recent selected studies related to the UPLC method and its method validation were summarized, and the results
of these studies with certain parameters obtained from literature were presented. Guzmán et al., contributed to our thematic
issue with a research paper entitled as “A Box-Behnken Optimized Methodology for the Quantification of Diclofenac using a Carbon
Paste-Multiwalled Carbon Nanotubes Electrode” . This paper presents the development of an optimized voltammetric
methodology for the quantification of diclofenac, which offers some advantages over other electrochemical and accepted methods.
In another contribution, “Electrochemical detection of ct-dsDNA on nanomaterial-modified carbon based electrodes” is reported
by Bozal-Palabiyik et al. . This paper reports preparation, characterization of two different nanomaterials and their electrochemical
application on double stranded calf-thymus DNA signals. Here, the multi-walled carbon nanotubes were functionalized with
amine groups (MWCNTs-NH2) by employing the dielectric barrier discharge plasma treatment. Both dsDNA modified electrodes
were employed to explore the interaction between the dsDNA and the anticancer drug etoposide in aqueous solution through
In the last contribution, again a research paper was appeared by Secci et al., entitled as “Investigation on the stability of new
biologically active thiosemicarbazone-derived compounds by a validated HPLC-PDA method” . This paper reports the development and validation of an HPLC-PDA method for the simultaneous determination and chemical-physical stability evaluation
after forced decomposition studies of thiosemicarbazone-derived compounds endowed with interesting pharmacological
We tried to combine different kinds of analyzing methods, discussed by different authors, to maintenance the riches of analytical
chemistry. Therefore, we believe that this thematic issue will be very useful for the readers that wanted to have broad
knowledge. We believe that you, as the valuable readers of Current Analytical Chemistry journal, will find out new information,
topic of interest, new ideas from this thematic issue and we hope that this thematic issue will encourage researches to
achieve analysis of pharmaceutical active compounds using different kinds of methods.
We would like to thank all of the authors one more time for their excellent contributions, the Editors of “CURRENT
ANALYTICAL CHEMISTRY” for this kind invitation to act as guest editors for this thematic issue and the valuable assistance
by Editorial Manager, Syed Faizan Akhtar in the processing and finalization of this special theme issue.
Analytical scientists due to unique properties of nanomaterials increased fabrications of nanostructure analytical sensors in
the recent years. Nano-materials with high surface area and good stability are good choice for improving sensitivity analytical
sensor for food, biological and pharmaceutical compounds analyses. Nano-material such as carbon nanotubes, metal oxide nanoparticles,
graphene, polymer nanostructures and etc. suggested for application in analytical techniques such as voltammetry,
spectroscopy, and chromatography. The published papers confirmed high quality of nanomaterials for improving trace level
analysis of important food, pharmaceutical and environmental analysis. Therefore, recent modified methods were used nanomaterials
as important part in fabrication of novel analytical sensors.
The scope of this issue focuses on the strategies for determination of food, biological, pharmaceutical and environmental
compounds using modified nanostructure sensors. This special issue included 7 reviews and 3 research article about application
of nanomaterials in fabrication of analytical sensors.
In paper 1, Faridbod et al., described a review paper about the graphene quantum dots in fabrication of electrochemical sensors/
biosensors. They discuss about the ways synthesis of graphene quantum dots and fabricated sensors or biosensors modified
with graphene quantum dots.
In paper 2, the electrochemical sensors modified with various nanomaterials discussed for determination of sulfonamides. In
this paper, history of developing voltammetric sensors based on nanomaterials for the detection of sulfonamides including sulfadiazine,
sulfamethoxazole, sulfacetamide, sulfadimethoxine, sulfathiazole, sulfamethiazole and sulfamerazine is reviewed.
In paper 3, new emerging one-dimensional nanostructure materials for gas sensing application described by Bharti et al.
This review focused for application of nanomaterials in fabrication of gas sensors.
In paper 4, the ability of metal-based nanoparticles as conductive mediators in electrochemical sensors was investigated.
The metal-based nanoparticles such as Au nanoparticle, Pt nanoparticle, Fe3O4 nanoparticle and etc. is reviewed by Karimi-
Maleh et al.
In paper 5, application of advanced electrochemical methods with nanomaterial-based electrodes as powerful tools for trace
analysis of drugs and toxic compounds is reviewed.
In paper 6, Pourbasheer et al discussed recent advanced in biosensors based nanostructure for pharmaceutical analysis (~ 73
In paper 7, development of novel nanocomposites based on graphene/graphene oxide and electrochemical sensor applications.
In the paper 8, simultaneous determination of epinephrine and tyrosine using a glassy carbon electrode amplified with ZnOPt/
CNTs nanocomposite described by Samadzadeh et al.
In paper 9, we describe application of CdO decorated single wall carbon nanotubes as a conductive nanomaterial for modification
of carbon paste electrode. The nanostructure sensor showed high sensitivity for determination of tertbutylhydroxyanisole
as a food antioxidant.
In paper 10, the role of NiO nanoparticle decorated single wall carbon nanotubes discussed for fabrication of new electrochemical
sensor for determination of mycophenolate mofetil by Hosseini et al.
I hope that in the special issue of Current Analytical Chemistry that collected in different fields relative to the application of
nanomaterial for fabrication of analytical sensors useful for readers.
Plasticizers are organic compounds added to polymers to facilitate processing and increase flexibility and toughness of the
final product by internal modification of the polymer molecule. Many plasticizers are considered as endocrine disruptors and
show activity on the reproductive system or act as carcinogens. They can be released into the environment through leaching
from final products and during manufacturing processes. The most commonly used plasticizers are phthalates, which comprise
approximately 90% of plasticizer production in the world. Since phthalates are not chemically bound to the materials they are
used in, they can be released from the products that contain them, for instance into water and air. There is public concern about
phthalates because of their widespread use and occurrence in the environment as well as their potential effects on human health.
Other organic contaminants highly used as plasticizers are alkylphenols, namely octylphenol and nonylphenol, bisphenol A or
benzophenone. The analysis of all these compounds relies on the use of methods allowing their unequivocal identification in
complex environmental matrices. Gas chromatography coupled to mass spectrometry or high-performance liquid chromatography
coupled with tandem mass spectrometry are the most commonly used techniques for the analysis of these compounds. Furthermore,
metabolomics, the comprehensive analysis of metabolites in a biological system, which provides detailed information
about the biochemical /physiological status of a biological system and the changes caused by chemicals, can be used to assess
the toxicity of food plasticizers.
Aim of this thematic issue on Biopolymers and Biocomposites: Chemistry and Technology in journal Current Analytical
Chemistry to disseminate critical review and research findings in the area of biopolymers and biocomposites focusing on the
chemistry and technology aspects of the materials. This special issue consists of research and review articles in the areas of
chemistry and technology of biopolymers and biocomposites contributed by experts from worldwide. In this special issue we
covered vast topics such as A review on phenolic resin, Thermo-mechanical properties of flax fibre reinforced composites,
Next generation biomimetic bone tissue engineering from PLA/CaCO3 composites, Nanocrystalline cellulose as reinforcement
for polymeric matrix nanocomposites and its potential applications: A Review, Seaweeds as renewable sources for biopolymers
and its composites: A review, Recent Advances in Silver Nanoparticle Containing Biopolymer Nanocomposites for Infectious
Disease Control – A Mini Review, On the Effects of Geometrical Shapes in Failure Modes in Natural – Conventional Fiber
Reinforced Composite Tube (A review), New Generation Antibacterial Nanofibrous Membrane for Potential Water Filtration,
Review of kenaf reinforced hybrid biocomposites: Potential in defence applications, and Starch Cellulosic Bio-composites: A
Sustainable and Multifunctional Material for Green Technology from leading experts from Malaysia, Canada, Saudi Arabia,
UK, UAE, Denmark, Australia, Libya, and Qatar.
We are highly thankful to all authors who contributed in to this special issue and make made our thoughtful idea possible in
to bring in reality. Besides, that we are also thankful to Bentham Science Publishers and their supporting team, especially Mr.
Syed Faizan Akhtar, for helping assisting us during preparation till finalization of our this thematic special issue.