Anti-Inflammatory Agents in Ageing and Age-Associated Diseases

Author(s): S. Bonovas, N. M. Sitaras

Journal Name: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Formerly Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents

Volume 5 , Issue 4 , 2006

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Ageing and inflammation might be considered as natural partners. Numerous mechanisms of an inflammatory basis for several age-associated diseases have been identified. Some markers of inflammation are already being integrated into clinical medicine. Furthermore, existent anti-inflammatory drugs and novel candidates have been found to specifically target inflammation pathways in the ageing processes. In this review, we focus on the current knowledge on the field, from the molecular and cellular level to the therapeutic potential of anti-inflammatory agents. First, we present several theories of ageing, in order to explore the involvement of inflammation and to define targets of intervention. Then, we discuss the current approaches and applications as well as the future trends in research regarding the involvement of antiinflammatory agents in the ageing processes.

Keywords: Ageing, anti-inflammatory agents, inflammation

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Article Details

Year: 2006
Published on: 01 March, 2012
Page: [365 - 373]
Pages: 9
DOI: 10.2174/187152306778772856
Price: $65

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