Abstract
We present a comprehensive but not exhaustive review of new trends in drug discovery and targets for cancer and AIDS which begins by highlighting the different historical stages of drug discovery from clinical diagnosis, natural compounds, serendipity and chemotherapy to the present age of modern experimental and computational techniques. The current state of the art of computer-aided drug design and selected recent applications to Cancer and AIDS are discussed. Novel targets and drugs in Cancer and AIDS are analyzed. In conclusion, future perspectives for drug discovery, design and therapeutics in cancer and AIDS are presented.
Keywords: HIV-1, non-nucleoside reverse transcriptase inhibitors (NNRTIs), chemokine co-receptors, anti-VEGF antibody, molecular modeling (MM)
Current Computer-Aided Drug Design
Title: Cancer and Aids: New Trends in Drug Design and Chemotherapy
Volume: 2 Issue: 3
Author(s): Carlton Anthony Taft and Carlos Henrique Tomich de Paula da Silva
Affiliation:
Keywords: HIV-1, non-nucleoside reverse transcriptase inhibitors (NNRTIs), chemokine co-receptors, anti-VEGF antibody, molecular modeling (MM)
Abstract: We present a comprehensive but not exhaustive review of new trends in drug discovery and targets for cancer and AIDS which begins by highlighting the different historical stages of drug discovery from clinical diagnosis, natural compounds, serendipity and chemotherapy to the present age of modern experimental and computational techniques. The current state of the art of computer-aided drug design and selected recent applications to Cancer and AIDS are discussed. Novel targets and drugs in Cancer and AIDS are analyzed. In conclusion, future perspectives for drug discovery, design and therapeutics in cancer and AIDS are presented.
Export Options
About this article
Cite this article as:
Anthony Taft Carlton and Henrique Tomich de Paula da Silva Carlos, Cancer and Aids: New Trends in Drug Design and Chemotherapy, Current Computer-Aided Drug Design 2006; 2 (3) . https://dx.doi.org/10.2174/157340906778226382
DOI https://dx.doi.org/10.2174/157340906778226382 |
Print ISSN 1573-4099 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6697 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Tumour Gene Therapy Monitoring Using Magnetic Resonance Imaging and Spectroscopy
Current Gene Therapy Patent Selections:
Recent Patents on Inflammation & Allergy Drug Discovery Benzofuran Small Molecules as Potential Inhibitors of Human Protein Kinases. A Review
Current Pharmaceutical Design Recent Progress in the Development of ATP-Competitive and Allosteric Akt Kinase Inhibitors
Current Topics in Medicinal Chemistry Tumor Angiogenesis and VEGFR-2: Mechanism, Pathways and Current Biological Therapeutic Interventions
Current Drug Metabolism Reduction of Oxidative/Nitrosative Stress in Brain and its Involvement in the Neuroprotective Effect of n-3 PUFA in Alzheimer’s Disease
Current Alzheimer Research Dietary and Plant Polyphenols Exert Neuroprotective Effects and Improve Cognitive Function in Cerebral Ischemia
Recent Patents on Food, Nutrition & Agriculture Smart Electrospun Nanofibers for Controlled Drug Release: Recent Advances and New Perspectives
Current Pharmaceutical Design Dysregulated Pathway Identification of Alzheimer's Disease Based on Internal Correlation Analysis of Genes and Pathways
Combinatorial Chemistry & High Throughput Screening Nucleic Acid-Based Therapeutics for Glioblastoma
Anti-Cancer Agents in Medicinal Chemistry The Biology of the Sodium Iodide Symporter and its Potential for Targeted Gene Delivery
Current Cancer Drug Targets Natural Molecules as Talented Inhibitors of Nucleotide Pyrophosphatases/ Phosphodiesterases (PDEs)
Current Topics in Medicinal Chemistry Von Willebrand Factor and Cardiovascular Disease: From a Biochemical Marker to an Attractive Therapeutic Target
Current Vascular Pharmacology Biomedical Applications of Glycoconjugates
Mini-Reviews in Medicinal Chemistry A Common Pathway for All Autoimmune Diseases? The Unholy Alliance of Environment, Cell Death and Nucleic Acids
Current Immunology Reviews (Discontinued) subject Index To Volume 2
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents Nanofibers: New Insights for Drug Delivery and Tissue Engineering
Current Topics in Medicinal Chemistry Pleiotropic Role of HSF1 in Neoplastic Transformation
Current Cancer Drug Targets Regulation of Cell Migration and Invasion by Specific Modules of uPA: Mechanistic Insights and Specific Inhibitors
Current Drug Targets Tumor Protein p63/microRNA Network in Epithelial Cancer Cells
Current Genomics