Abstract
The term dietary fibre describes a wide range of highly divergent (mainly polysaccharide) compounds that escape digestion before the colon. Fibre is often regarded as a neutral dietary compound, not interacting with the gut and only offering dietary benefit by the consequent absence of calorific macronutrients, or by bulking out luminal content. Although the above benefits are apparent, a number of other physiological effects of dietary fibres in the colon have previously been described. This review outlines these previous observations in terms of the effect of various fibre types on (i) colonic luminal contents (including the resident microflora (ii) the first line of colonic protection, the mucus barrier (iii) the underlying colonic mucosa (iv) the colonic musculature and (v) colonic neurohumoural release, and the subsequent effect on control of gut motility and satiety. This review will further highlight the divergent physiological effects of various fibre types, and their potential health benefits.
Keywords: Dietary fibre, colon, mucus, satiety, PYY, morphology
Current Nutrition & Food Science
Title: The Interaction of Dietary Fibres with the Colon
Volume: 2 Issue: 3
Author(s): Iain A. Brownlee, Peter W. Dettmar, Vicki Strugala and Jeff P. Pearson
Affiliation:
Keywords: Dietary fibre, colon, mucus, satiety, PYY, morphology
Abstract: The term dietary fibre describes a wide range of highly divergent (mainly polysaccharide) compounds that escape digestion before the colon. Fibre is often regarded as a neutral dietary compound, not interacting with the gut and only offering dietary benefit by the consequent absence of calorific macronutrients, or by bulking out luminal content. Although the above benefits are apparent, a number of other physiological effects of dietary fibres in the colon have previously been described. This review outlines these previous observations in terms of the effect of various fibre types on (i) colonic luminal contents (including the resident microflora (ii) the first line of colonic protection, the mucus barrier (iii) the underlying colonic mucosa (iv) the colonic musculature and (v) colonic neurohumoural release, and the subsequent effect on control of gut motility and satiety. This review will further highlight the divergent physiological effects of various fibre types, and their potential health benefits.
Export Options
About this article
Cite this article as:
Brownlee A. Iain, Dettmar W. Peter, Strugala Vicki and Pearson P. Jeff, The Interaction of Dietary Fibres with the Colon, Current Nutrition & Food Science 2006; 2 (3) . https://dx.doi.org/10.2174/157340106778017896
DOI https://dx.doi.org/10.2174/157340106778017896 |
Print ISSN 1573-4013 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3881 |
Call for Papers in Thematic Issues
Functional Foods in Human Health and Beyond
Foods are important source of nutrients including carbohydrates, proteins, lipids and other minerals. Furthermore, the functional foods are those agents that have additional components that are essential supports to the body in terms of antioxidant and pharmacologically active agents. The predominant functional foods are of plant in origin, whereas some ...read more
Harnessing Bioactive Compounds from Food Waste: Sustainable Extraction Strategies and Health Applications
Food waste presents a significant challenge across the postharvest cycle, from agricultural production to distribution. However, within this waste lies a treasure trove of bioactive chemicals that hold immense potential for nutraceuticals, functional foods, and postharvest additives, including antimicrobials. Various extraction methods, such as solvent extraction (SE), supercritical fluid extraction ...read more
Natural Bioactive Compounds Derivatives in Nutraceutical and Food Science
In the last years, plants have been widely used for their numerous properties and now there is growing interest in the study of classes of compounds obtained from plant species or derived from them. The importance of these natural compounds lies in their important therapeutic purposes, and in their capability ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Novel Therapeutic Approaches Targeting Matrix Metalloproteinases in Cardiovascular Disease
Current Topics in Medicinal Chemistry Oxidative Stress in Essential Hypertension
Current Pharmaceutical Design Pharmacogenetics of the Metabolic Disturbances and Atherosclerosis Associated with Antiretroviral Therapy in HIV-Infected Patients
Current Pharmaceutical Design Neutrophil F-actin Dynamics in Familial Mediterranean Fever: The Unequal Effect of Colchicine on Activated Neutrophils
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Strategies for Effective Naked-DNA Vaccination Against Infectious Diseases
Recent Patents on Anti-Infective Drug Discovery The Critical Role of Vascular Endothelial Growth Factor in Tumor Angiogenesis
Current Cancer Drug Targets Antiplatelet Therapy in Acute Coronary Syndromes. Evidence Based Medicine
Current Pharmaceutical Design Advances in the Treatment of Neurodegenerative Disorders Employing Nanoparticles
Recent Patents on Drug Delivery & Formulation Editorial (Hot Topic: Cardiovascular Disease Biomarkers: from Tradition to Modernity)
Current Topics in Medicinal Chemistry Targets and Patented Drugs for Chemotherapy of Chagas Disease in the Last 15 Years-Period
Recent Patents on Anti-Infective Drug Discovery Heparin Oligosaccharides as Potential Therapeutic Agents in Senile Dementia
Current Pharmaceutical Design Editorial (Novel Therapies and Botanical and Mechanical Approaches for Management of Cardiovascular Disease)
Recent Patents on Cardiovascular Drug Discovery Coumarins as Promising Scaffold for the Treatment of Age-related Diseases – An Overview of the Last Five Years
Current Topics in Medicinal Chemistry The Role of Infection in Carotid Plaque Pathogenesis and Stability: The Clinical Evidence
Current Vascular Pharmacology Salvaging the Ischemic Heart: Gi-Coupled Receptors in Mast Cells Activate a PKCε/ALDH2 Pathway Providing Anti-RAS Cardioprotection
Current Medicinal Chemistry Synthesis and Bioactivity of (R)-Ricinoleic Acid Derivatives: A Review
Current Medicinal Chemistry Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In vivo, In vitro and Network Analyses
Recent Patents on Anti-Cancer Drug Discovery Pharmacological Treatments for Obesity
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Diet, Cardiometabolic Factors and Type-2 Diabetes Mellitus: The Role of Genetics
Current Diabetes Reviews Patent Selections:
Recent Patents on Anti-Cancer Drug Discovery