The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator

Author(s): Ana C. S. e Silva, Sergio V. B. Pinheiro, Regina M. Pereira, Anderson J. Ferreira, Robson A. S. Santos

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 5 , 2006

Become EABM
Become Reviewer
Call for Editor


In this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin II and exerts complex renal actions. We also speculate the possibility of new drugs for the treatment of cardiovascular, genitourinary and hepatic diseases by interfering with ACE2- Angiotensin-(1-7)-Mas axis.

Keywords: Angiotensin-(1-7), Mas receptor, Angiotensin-converting enzyme 2, Angiotensin II, AVE 0991, Angiotensin antagonists, Renin-Angiotensin System

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2006
Page: [603 - 609]
Pages: 7
DOI: 10.2174/138955706776876203
Price: $65

Article Metrics

PDF: 14