Abstract
The lung is a very attractive target for drug delivery. Currently, as direct access for the treatment of lower respiratory diseases. Possibly, in the future, as the route of administration for systemic therapies. Nebulizers are widely used throughout the world in adult and padiatric medical practice. They are used for the management of acute bronchoconstriction both at home and in hospital, but also for long-term home treatment of various lower respiratory diseases, mainly in elderly and in infants. Overall, bronchodilators are the first class of drugs used by nebulization. The efficiency of the nebulizer has to be assured mainly for suspension, such as corticosteroids, and hyperviscous solution, such as antimicrobials, which aerolize with more difficulties with respect to bronchodilators. Unfortunately, knowledge on the optimal use of nebulizers is limited. Guidelines on best nebulizer practice are often lacking. There is a need to establish some guidance for both the drug and nebulizer manufacturers and prescribing physicians for optimization of nebulizer therapy, individuating not only drugs, dosing and administration schedule, but also the effective nebulizer system and the method for its optimal use and maintenance.
Keywords: Aerosol therapy, nebulizer, inhalation therapy, COPD, asthma
Current Respiratory Medicine Reviews
Title: Nebulizer Therapy in Pulmonology: Review of the Literature
Volume: 2 Issue: 2
Author(s): Andrea S. Melani and Letizia S. Bracci
Affiliation:
Keywords: Aerosol therapy, nebulizer, inhalation therapy, COPD, asthma
Abstract: The lung is a very attractive target for drug delivery. Currently, as direct access for the treatment of lower respiratory diseases. Possibly, in the future, as the route of administration for systemic therapies. Nebulizers are widely used throughout the world in adult and padiatric medical practice. They are used for the management of acute bronchoconstriction both at home and in hospital, but also for long-term home treatment of various lower respiratory diseases, mainly in elderly and in infants. Overall, bronchodilators are the first class of drugs used by nebulization. The efficiency of the nebulizer has to be assured mainly for suspension, such as corticosteroids, and hyperviscous solution, such as antimicrobials, which aerolize with more difficulties with respect to bronchodilators. Unfortunately, knowledge on the optimal use of nebulizers is limited. Guidelines on best nebulizer practice are often lacking. There is a need to establish some guidance for both the drug and nebulizer manufacturers and prescribing physicians for optimization of nebulizer therapy, individuating not only drugs, dosing and administration schedule, but also the effective nebulizer system and the method for its optimal use and maintenance.
Export Options
About this article
Cite this article as:
Melani S. Andrea and Bracci S. Letizia, Nebulizer Therapy in Pulmonology: Review of the Literature, Current Respiratory Medicine Reviews 2006; 2 (2) . https://dx.doi.org/10.2174/157339806776843067
DOI https://dx.doi.org/10.2174/157339806776843067 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Diagnosis of Large Airway Pathology and the Role of Rigid Bronchoscopy
Current Respiratory Medicine Reviews Vascular Effects of Antiarrhythmic Drugs and the Roles of K+ Channels
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Molecular Biological Roles of Ursolic Acid in the Treatment of Human Diseases
Current Bioactive Compounds Statins and Left Ventricular Function
Current Pharmaceutical Design Further Issues with New Oral Anticoagulants
Current Pharmaceutical Design Effects of Verbascoside Administration on the Blood Parameters and Oxidative Status in Jennies and Their Suckling Foals: Potential Improvement of Milk for Human Use
Endocrine, Metabolic & Immune Disorders - Drug Targets Gene-Activators Prevent and Regress Atherosclerosis and Reduce Mortality
Cardiovascular & Hematological Agents in Medicinal Chemistry Therapeutic Strategies for Treatment of Inflammation-related Depression
Current Neuropharmacology Naturally Occurring Hydroxytyrosol: Synthesis and Anticancer Potential
Current Medicinal Chemistry Infections and Atheromatous Plaque: Current Therapeutic Implications
Current Pharmaceutical Design Metabolic Syndrome and Asthma
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Calcium Antagonists: A Ready Prescription for Treating Infectious Diseases?
Current Topics in Medicinal Chemistry Derivatives of 1,2,3,4-tetrahydroisoquinoline-7-carboxylic Acid as Novel Fibrinogen Receptor Antagonists
Medicinal Chemistry A Rationale for Curcuminoids for the Prevention or Treatment of Alzheimers Disease
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents The Real Code of Leonardo da Vinci
Current Cardiology Reviews Balaglitazone: A Second Generation Peroxisome Proliferator-Activated Receptor (PPAR) Gamma (γ) Agonist
Mini-Reviews in Medicinal Chemistry Markers of Arrhythmogenic Risk in Hypertensive Subjects
Current Pharmaceutical Design Role of Heme Oxygenase-1 in Cardiovascular Function
Current Pharmaceutical Design Effect of Nigella Sativa and Allium Sativum Coadminstered with Simvastatin in Dyslipidemia Patients: A Prospective, Randomized, Double-Blind Trial
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Challenges and Promises of Developing Thrombin Receptor Antagonists
Recent Patents on Cardiovascular Drug Discovery