Enzymatic Biosynthesis of Oligosaccharides and Glycoconjugates

Author(s): Jing Song, Houcheng Zhang, Lei Li, Zishu Bi, Min Chen, Wei Wang, Qingjia Yao, Hongjie Guo, Min Tian, Hanfen Li, Wen Yi, Peng George Wang

Journal Name: Current Organic Synthesis

Volume 3 , Issue 2 , 2006

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Abstract:

Natural carbohydrates have complex structures including many kinds of monosaccharide units, which are very difficult and costly to generate by chemical synthetic approaches. Over the years, enzymatic approaches have been gaining popularity for the synthesis of oligosaccharides and glycoconjugates, and it is becoming increasingly feasible to produce complex carbohydrates in large scale, following enzymatic biosynthetic pathways.

Keywords: Glycosidases, sugar nucleotides, glycosyl donors, UDP, –, N -acetylglucosamine, Glycosyltransferases

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Article Details

VOLUME: 3
ISSUE: 2
Year: 2006
Page: [159 - 168]
Pages: 10
DOI: 10.2174/157017906776819187
Price: $65

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