Geminin as A Molecular Target for the Development of New Anticancer Drugs

Author(s): Kenichi Yoshida

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 4 , 2006

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Abstract:

The unique biological properties of Geminin, particularly as an inhibitor of DNA replication initiation, have been recognized, and this has prompted a number of investigations into this molecule to explore its potential therapeutic as well as diagnostic usefulness. This review summarizes the possibility of Geminin serving as a new molecular target in the development of new anticancer drugs.

Keywords: Geminin, Cdt1, DNA replication, Cancer cell, Peptide

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Article Details

VOLUME: 6
ISSUE: 4
Year: 2006
Page: [461 - 462]
Pages: 2
DOI: 10.2174/138955706776361411
Price: $65

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