Towards the Targeted Therapy of Melanoma

Author(s): K. S.M. Smalley, M. Herlyn

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 4 , 2006


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Abstract:

Novel anti-cancer treatments use knowledge about the underlying biology of the tumor to find suitable molecular targets. The recent years have seen great advances in understanding the biology of melanoma. In the current review we discuss the most promising molecular targets for melanoma and suggest possible strategies for overcoming resistance.

Keywords: Melanoma, melanocyte, BRAF, PI3K, therapy, cancer, proteasome

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Article Details

VOLUME: 6
ISSUE: 4
Year: 2006
Page: [387 - 393]
Pages: 7
DOI: 10.2174/138955706776361402
Price: $65

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