Improved Sensory Blockade by Clonidine Added to Axillary Block Solution. Resulting Plasma Clonidine Concentration

Author(s): Jean-Marc Bernard

Journal Name: Letters in Drug Design & Discovery

Volume 3 , Issue 2 , 2006

Become EABM
Become Reviewer

Abstract:

In this prospective, randomized, double-blinded study, clonidine was found an efficient adjunct to local anesthetics for increasing the intensity of axillary brachial plexus block. Similar clonidine dose had no such effect when administered intramuscularly, suggesting a local, neural effect. Blood absorption was similar in both cases, leading to central action as sedation.

Keywords: Adrenergic agonists, adrenergic a-agonists, anesthesia, conduction, nerve block, pharmacology, plasma clonidine concentration

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 3
ISSUE: 2
Year: 2006
Page: [87 - 90]
Pages: 4
DOI: 10.2174/157018006775789739
Price: $65

Article Metrics

PDF: 1