The Role of Kinetics in High Throughput Screening for Drugs
Pp. 167-195 (29)
Agustina Gomez-Hens, M Paz Aguilar-Caballos
A systematic study of the incidence of kinetics in high throughput screening for drug design and discovery is presented and discussed. This study includes dynamic aspects of the techniques and assays used in this complex research field, kinetic methods applied to the selection of drug candidates, and recent advances in the elucidation of drug-receptor interaction mechanisms and in high throughput pharmacokinetic screening.