Reviews in Pharmaceutical & Biomedical Analysis

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Reviews in Pharmaceutical and Biomedical Analysis contains coverage and review of new trends and applications in all areas of pharmaceutical, biomedical and analytical chemistry. Authors have ...
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Microbial Cells and Biosensing: A Dual Approach - Exploiting Antibodies and Microbial Cells as Analytical/Power Systems

Pp. 63-75 (13)

Sushrut Arora, Gabriele Pastorella, Byrne Barry, Marsili Enrico and Richard O Kennedy

Abstract

The primary focus of this review is the discussion of how biosensor-based platforms can be used in conjunction with microbial cells for monitoring, environmental and industrial applications. Two approaches will be comprehensively discussed. The first of these will examine how immunosensors can be used for the sensitive and selective detection of bacterial pathogens in a range of diverse and complex sample matrices. Secondly, we discuss the implementation of free and immobilised microbial cells for facilitating the analysis of chemicals and metabolites in cost-effective devices that, in turn, are directly applicable to environmental monitoring. Further examples, relating to the uses and advantages of microbial fuel cells are also discussed, with particular emphasis on recent and innovative developments.

Affiliation:

School of Biotechnology, Dublin City University, Dublin 9, Ireland; Biomedical Diagnostics Institute (BDI),Dublin City University, Dublin 9, Ireland; Centre for Bioanalytical Sciences (CBAS), Dublin City University,Dublin 9, Ireland and National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9, Ireland