New Developments in Medicinal Chemistry

Volume: 1

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This book is recommended for readers who are interested in or work with current theoretical and experimental research in medicinal chemistry, with an emphasis on computer aided-drug design and ...
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General Aspects of the Microwave-Assisted Drug Development

Pp. 114-132 (19)

Peterson de Andrade, Lilian Sibelle Campos Bernardes and Ivone Carvalho


Microwaves are a powerful and reliable energy sources that may be adapted to many applications. Since the introduction of microwave-assisted organic synthesis in 1986, the use of microwave irradiation has now introduced a completely new approach to drug discovery. The efficiency of microwave flash-heating chemistry in dramatically reducing reaction times has recently fascinated many pharmaceutical companies, which are incorporating microwave chemistry into their drug development efforts. Thereby, the time saved by using microwaves is important for accelerating traditional organic synthesis or high-speed medicinal chemistry.


School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Av. do Cafe, s/n, Monte Alegre, 14040-903, Ribeirao Preto, Sao Paulo, Brazil.