Contemporary Sleep Medicine For Physicians

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Contemporary Sleep Medicine should be of interest to a large number of readers interested in sleep medicine. It is divided into two parts – one for patients or simple readers and another for ...
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Medications and Sleep

Pp. 247-258 (12)

Francoise J. Roux and Meir H. Kryger


Sleep is essential for optimal mental, physical and social wellbeing (or, generically, health). Sleep disruption and/or deprivation can have adverse health consequences, promoting or worsening cardiovascular disease and diabetes. The sleep-wake cycle is a very tightly regulated process that involves multiple neuropharmacological reciprocal interactions. It was recently shown that sleep deprivation and sleep disorders can have adverse metabolic consequences. Multiple medications have a direct or indirect impact on sleep and the waking state. In this article, we review the effects of commonly prescribed medications on the sleep-wake cycle.


Assistant Professor of Medicine, Section of Pulmonary and Critical Care Medicine, Yale, University School of Medicine, 333 Cedar Street, Post Office Box 208057, New Haven, CT 06520-8057, USA.