Multiple Myeloma - A New Era of Treatment Strategies

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Multiple Myeloma (MM), the second most common blood cancer in adults, is a clonal plasma cell malignancy within the bone marrow characterized by osteolytic bone lesions, renal disease, and ...
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Management of Complications in Multiple Myeloma

Pp. 107-119 (13)

DOI: 10.2174/978160805297411201010107

Author(s): Suzanne Lentzsch


Patients with multiple myeloma have a high rate of complications related to their underlying disease. This includes anemia, renal failure, complications related to bone disease such as hypercalcemia, bone pain and fractures, infection and renal insufficiency. Adequate supportive care is therefore an essential part of each anti-myeloma treatment and can significantly improve overall survival and the quality of life of multiple myeloma patients. This review focuses on the management of specific complications associated with advanced multiple myeloma.


Bone disease, hypercalcemia, pain, kyphoplasty, vertebroplasty, osteonecrosis of the jaw (ONJ), infections, renal insufficiency, anemia.