The Use of Electronic Nose Devices in Clinical Microbiology
Pp. 90-101 (12)
M. Bruins, A. van Belkum and A. Bos
This chapter describes the use of electronic noses in the field of clinical microbiology. These
devices can be used to detect volatile organic compounds directly from clinical materials and can also
be applied to monitor the production of volatiles during the process of microbiological culture. Various
electronic nose appliances have been developed, but most need rigorous normalization and
standardization each and every time that the sensors are renewed. In this chapter, the authors focus on a
recently developed, patented micro-technology that does not require regular normalization. Using metal
oxide sensors and electronic nose technology allows the dynamic analysis of volatile molecule
production during bacterial fermentation to be performed, which will facilitate the real-time detection
and identification of live bacteria present within clinical specimens.
Electronic Nose, Smell, Quartz Microbalance, Conducting Polymers, Semi-conducting Metal
Oxides, MonoNose, Pattern Fingerprints.
C-it BV, Marspoortstraat 2, 7201 JB Zutphen, The Netherlands.