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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Mini-Review Article

Update on Modulators of Quorum Sensing Pathways in Pseudomonas aeruginosa

Author(s): Mohammad Anwar Hossain and Nadezhda A. German*

Volume 21, Issue 23, 2021

Published on: 24 September, 2021

Page: [2101 - 2108] Pages: 8

DOI: 10.2174/1568026621666210924160004

Price: $65

Abstract

Modulators of quorum sensing pathways in Pseudomonas aeruginosa (PA) gain attention due to their potential therapeutic applications. These chemical agents are viewed as anti-virulence agents capable of increasing the existing therapeutic agents’ efficacy against resistant clinical strains. Additionally, they can be utilized in developing anticancer therapeutics, whole-cell biosensors, and artificial biological systems. In this mini-review, we summarize recent (2015-2021) publications on PA's QS modulation.

Keywords: Pseudomonas aeruginosa, virulence factors, quorum sensing, quorum sensing inhibitors.

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