Recent Developments in the Synthesis of Five- and Six-membered N-heterocycles from Dicarbonyl Compounds

Author(s): Navjeet Kaur*, Pranshu Bhardwaj, Mansi Gupta

Journal Name: Current Organic Chemistry

Volume 25 , Issue 22 , 2021


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Abstract:

Various diketones such as 1,2-diketones, 1,3-diketones, 1,4-diketones, β- diketones and dicarbonyl compounds are used in the synthesis of core heterocyclic compounds such as pyrazoles, isoxazoles, triazoles and quinolones. They play an important role in synthetic organic chemistry. The diketones and dicarbonyl compounds also act as chelating ligands for the lanthanides and a large number of transition metals in material chemistry. 50% of drugs contain nitrogen heterocyclic compounds, so organic chemists have made efforts for the synthesis of nitrogen-containing heterocyclic compounds. This review article has compiled different methodologies for the synthesis of five- and six-membered nitrogencontaining heterocyclic compounds.

Keywords: Synthesis, dicarbonyl compounds, diketones, nitrogen, heterocycles, six-membered.

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Article Details

VOLUME: 25
ISSUE: 22
Year: 2021
Published on: 11 August, 2021
Page: [2765 - 2790]
Pages: 26
DOI: 10.2174/1385272825666210812102416
Price: $95

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