N,N-Dimethylformamide (DMF): An Inexpensive and Attractive Reactant

Author(s): Xiao-hua Cai*, Hui Guo

Journal Name: Current Organic Chemistry

Volume 25 , Issue 17 , 2021


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Abstract:

The development of simple, atom-economical, and sustainable methodologies for the construction of various functional molecules from easily available substrates has been of great interest in synthetic chemistry. N,N-dimethylformamide (DMF) is an inexpensive, abundant solvent and industrial raw material, and it is considered as an effective polar solvent and also as a versatile reagent in synthetic transformations. During the past few decades, many significant and attractive achievements have been made in the fields of DMF as a reactant. The mini-review will mainly summarize recent advance in the applicants of DMF as a multipurpose building block in synthetic reactions.

Keywords: N, N-dimethylformamide, DMF, building block, organic solvent, versatile reactant, synthetic transformation, synthetic chemistry.

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Article Details

VOLUME: 25
ISSUE: 17
Year: 2021
Published on: 25 June, 2021
Page: [1977 - 2004]
Pages: 28
DOI: 10.2174/1385272825666210625115100
Price: $65

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