Functional Group Interconversion Reactions in Continuous Flow Reactors

Author(s): Alexander Leslie, Angel Maria Joseph, Marcus Baumann*

Journal Name: Current Organic Chemistry

Volume 25 , Issue 19 , 2021

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Graphical Abstract:


An overview of the current uptake of continuous flow techniques for various functional group interconversion reactions is presented. Besides highlighting a variety of prominent examples and their main features, this review provides insights into specific reaction classes, such as oxidations, reductions, rearrangements as well as different C-H functionalization processes. While this review can only include key examples from the last decade, the reader will find a solid foundation of important transformations along with further references to inform and appreciate the opportunities arising from modern synthesis technologies such as flow synthesis.

Keywords: Flow synthesis, functional group interconversion, oxidation, reduction, rearrangement, C-H functionalization.

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Article Details

Year: 2021
Published on: 06 July, 2021
Page: [2217 - 2231]
Pages: 15
DOI: 10.2174/1385272825666210610154414
Price: $65

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PDF: 324