Abstract
We provide a brief review of the significance of platelets, mitochondria, vitamin D, serotonin, and the gut microbiome in COVID-19. We hypothesize that hyperactive platelets and mitochondrial dysfunction, as well as low vitamin D level, gut dysbiosis, and increased serum serotonin produced by enterochromaffin cells, may all represent important aspects in the pathophysiology of COVID-19.
Keywords: Platelets, mitochondria, vitamin D, serotonin, gut-brain axis, COVID-19, SARS-CoV-2.
Current Medicinal Chemistry
Title:COVID-19: The Significance of Platelets, Mitochondria, Vitamin D, Serotonin and the Gut Microbiota
Volume: 28 Issue: 37
Author(s): István Bókkon*, Gábor Kapócs, András Vucskits, Attila Erdöfi-Szabó, Jan Vagedes , Felix Scholkmann and Henrik Szöke
Affiliation:
- Vision Research Institute, Neuroscience and Consciousness Research Department, Lowell, MA,United States
Keywords: Platelets, mitochondria, vitamin D, serotonin, gut-brain axis, COVID-19, SARS-CoV-2.
Abstract: We provide a brief review of the significance of platelets, mitochondria, vitamin D, serotonin, and the gut microbiome in COVID-19. We hypothesize that hyperactive platelets and mitochondrial dysfunction, as well as low vitamin D level, gut dysbiosis, and increased serum serotonin produced by enterochromaffin cells, may all represent important aspects in the pathophysiology of COVID-19.
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Cite this article as:
Bókkon István*, Kapócs Gábor , Vucskits András , Erdöfi-Szabó Attila , Vagedes Jan , Scholkmann Felix and Szöke Henrik , COVID-19: The Significance of Platelets, Mitochondria, Vitamin D, Serotonin and the Gut Microbiota, Current Medicinal Chemistry 2021; 28 (37) . https://dx.doi.org/10.2174/0929867328666210526100147
DOI https://dx.doi.org/10.2174/0929867328666210526100147 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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