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CNS & Neurological Disorders - Drug Targets

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ISSN (Online): 1996-3181

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Review Article

Dietary Nutrients and Prevention of Alzheimer’s Disease

Author(s): Pallavi Singh Chauhan, Dhananjay Yadav* and Ananta Prasad Arukha

Volume 21, Issue 3, 2022

Published on: 05 April, 2021

Page: [217 - 227] Pages: 11

DOI: 10.2174/1871527320666210405141123

Price: $65

Abstract

Alzheimer’s disease is an irrevocable, progressive brain disorder that gradually destroys memory and cognitive skills. One of the extensively studied methods of preventing Alzheimer’s disease (AD) progression is by providing a nutritional diet. Several reports have shown that intake of nutritional elements as huperzine A, ursolic acid, vitamins etc., can directly influence pathogenesis of AD. Surprisingly, the occurrence of metabolic disorders due to an unhealthy diet has been known to be a major environmental cause of AD. It has been noted that AD severity can be controlled by supplementing dietary supplements containing huge amounts of health-promoting ingredients. These elements promote cell health, regeneration, and the anti-aging process that specifically interrupt the pathogenic pathways in AD development. Fortunately, incorporating changes in the nutritional content is inexpensive, easy, acceptable, safe, effective, and in most cases, free from major adverse events. Many nutritional phytoconstituents such as flavonoids, alkaloids, and terpenoids are still being evaluated in the hope of identifying a successful therapy for AD. This review discusses the therapeutical potential of several key nutrients that have been researched for treating AD treatment and the method of their neuroprotective intervention.

Keywords: Alzheimer’s Disease, nutrition, oxidative stress, neurodegeneration, inflammation, brain disease.

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