The demand for various unconventional foods to reduce the complications in both communicable
and non-communicable diseases is increasing day by day. The aim of this review was to
observe the efficacy of Aloe vera in hyperglycemia and in hyperlipidemia in vivo (both animals and
humans). The studies of different authors were searched by using many scientific search engines
such as Pub Med, Google Scholar, Science Direct, the database of Open Access Journals. There are
25 animal studies and 10 human studies included in this review. By analyzing data, data were extracted
from selected articles that showed the effects of a different form of Aloe vera on diabetes
and hyperlipidemia after consumption. The result of this review covers different doses and forms
of Aloe vera, which were provided to target animals and humans for a different duration to achieve
an outcome in those articles. Most of the studies showed a significant result that means Aloe vera
has a positive effect on diabetes and hyperlipidemia. Further studies are needed to elucidate the
pathophysiological mechanisms of action of Aloe vera as well as its efficacy and safety in the
treatment of various diseases.
Keywords: Aloe vera, diabetes mellitus, hyperlipidemia, mice, human, clinical trial.
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